• What can be done to reduce morbidity and mortality in

  2019-06-24

  

  What can be done to reduce morbidity and mortality in HEU infants? Notably, a third of all mortality in the Botswana trial occurred early, before randomisation. Similarly, in a trial of more than 14 110 infants in Zimbabwe, done in the pre-MTCT-prevention era, HIV-exposed uninfected infants had 50%

• br Methods br Results br Discussion ICC represents

  2019-06-24

  

  Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi

• br CaMKII and heart failure progression CaMKII is a

  2019-06-24

  

  CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com

• Moving forward we identify several urgent

  2019-06-24

  

  Moving forward, we identify several urgent needs and challenges. First, the standing of IMD 0354 health workers in the health-care systems needs to be legitimised and moved away from largely grant-funded temporary employees or volunteers who might provide educational services towards skilled member

• De acuerdo con esto la mejor

  2019-06-24

  

  De acuerdo con esto, la mejor parábola es la custodia dorada que contiene un dios vivo y dado Bexarotene structure ver a los creyentes en la fiesta del Corpus: pura discursividad expuesta y directa que no permite más alegoría que su propia clausura, que no permite más fábula que éste su hacerse en p

• Otra cuesti n que debi afrontar la pol tica exterior

  2019-06-24

  

  Otra cuestión que debió afrontar la política exterior argentina fue la necesidad de recuperar la inserción del país en Latinoamérica. En el abordaje de esta cuestión, como en la referida JTC-801 las situaciones de dependencia, la política exterior contó con un contexto internacional muy permisivo, g

• El n mero de correspondiente al segundo semestre

  2019-06-24

  

  El número 59 de , correspondiente al segundo semestre de 2014, ofrece la sección Temas y Problemas de Nuestra América, en el que se encuentran artículos relacionados con asuntos de gran relevancia actual. En primer lugar, el texto “Nuevas narrativas constitucionales en Bolivia y Ecuador: el buen viv

• bromodomain br Discussion To our knowledge we report for

  2019-06-24

  

  Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p

• br Discussion Case reports of

  2019-06-24

  

  Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy,

• br In a reanalysis of

  2019-06-24

  

  In a reanalysis of our results, Michelle Remme and colleagues (October, 2015) found that “secondary schooling might [even] be as good an HIV investment as male circumcision”, not to mention more expensive biomedical options. As Remme and colleagues rightly point out, we had excluded from our cost-

• Perhaps counter intuitively the most

  2019-06-24

  

  Perhaps counter-intuitively, the most strategic tobacco control policies to reduce adolescent smoking and secondhand smoke exposure in LMICs may not be those targeting adolescents. Targeted campaigns can be expensive, and are unlikely to be as effective as the more affordable tobacco control policie

• br Conflict of interest br Acknowledgments

  2019-06-24

  

  Conflict of interest Acknowledgments This research was supported by the Grants from the National Natural Science Foundation of China (No. 31270820 and No. 81230061 to Wei-Dong Han, No. 81402567 to Ya-jing Zhang) and was partially supported by a Grant from the National Basic Science and Develop

• Desde la perspectiva expuesta la

  2019-06-21

  

  Desde la perspectiva expuesta, la etnicidad constituye una dimensión potencial de la identidad, fundamentada en un conjunto de elementos que, al seguir la tradición weberiana, pueden abarcar la percepción de origen, cultura, idioma o rasgos fenotípicos compartidos por un conjunto de personas. La adq

• The characteristics of the tumors are

  2019-06-21

  

  The characteristics of the tumors are shown in Table 2. The tumor morphology indicated 69 (74%) exophytic tumors and 24 (26%) endophytic tumors. Forty-five patients (48%) had anterior commissure invasion, and 30 (32%) had tumors extending to the contralateral true vocal fold. Twenty-two patients (24

• Introduction Brugada syndrome is severe arrhythmia character

  2019-06-21

  

  Introduction Brugada syndrome is severe arrhythmia characterized by specific ST elevations in precordial leads and sudden ventricular fibrillation (VF), and the condition may result in sudden cardiac death [1–5]. By implanting defibrillation devices, also known as implantable cardioverter-defibrill

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