To evaluate possible genomic rearrangement and

2018-10-20

To evaluate possible genomic rearrangement and CNV of ATM in individual cells, we used a fluorescence in situ hybridization (FISH) probe specific for the ATM gene (chr11:108,089,374–108,241,929 in the hg19 genome). Results indicated that a majority of R-115777 had an equal number of ATM-specific pun

The antitumor potential of iNKT cells has

2018-10-20

The antitumor potential of iNKT cytoskeleton has been demonstrated in several clinical trials (Chang et al., 2005; McEwen-Smith et al., 2015; Motohashi et al., 2006, 2009; Nicol et al., 2011; Richter et al., 2013; Song et al., 2009; Uchida et al., 2008; Yamasaki et al., 2011). Infiltration of iNKT

Comparative analysis of transgenic hPAX GFP

2018-10-20

Comparative analysis of transgenic hPAX6GFP expression revealed similarities between the retinal organoid system and the mouse retina in vivo. Our analyses indicated a similar sequence of hPAX6GFP+ retinal cell types in mice in vivo, and in mESC- and hESC-derived retinal organoids: progenitors and r

cysteine protease inhibitor Mosaicism in CGG repeat length

2018-10-20

Mosaicism in CGG repeat length is often observed in FXS patients, who carry both premutation and full mutation cysteine protease inhibitor and therefore differ in the proportion of cells with silenced FMR1, which contributes to the clinical spectrum of FXS phenotypes (Rousseau et al., 1994). Mosaic

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2018-07-29