• The site of metastasis in breast cancer often

  2021-11-01

  

  The site of metastasis in breast cancer often contributes to the patient’s OS. Patients with bone metastasis from their breast cancer often have a notably increased survival over patients with visceral or Capecitabine metastasis. In this analysis, ER+/HER2+ patients were noted to have a higher rate

• In humans polymorphisms in the lengths

  2021-11-01

  

  In humans, polymorphisms in the lengths of GT sequences (from 11 to 40) within the HMOX1 promoter impact the magnitude of HO-1 expression profiles. Long GT repeats code for less stable (Z-conformational) DNA with blunted transcriptional activity resulting in lower resting and stimulated HO-1 protein

• br Conclusion br Conflict of interest Please refer to the

  2021-11-01

  

  Conclusion Conflict of interest Please refer to the accompanying ICMJE disclosure forms for further details. Exotic species such as hedgehogs are becoming popular companion animals. Therefore, they are more commonly seen in veterinary clinics. Acariasis is fairly common in these animals, us

• Small but statistically significant variance in PhyChem inde

  2021-11-01

  

  Small but statistically significant variance in 7 PhyChem indexes measured using intra-host HVR1 variants was shown to be strongly associated with CIP and MIP. All HVR1 sequences (N = 28,622) used here share only 6782 profiles of the selected 29 DAC’ of 7 PhyChem indexes. The significant majority (9

• The expression of heat shock proteins

  2021-10-29

  

  The expression of heat-shock proteins (HSPs) can be upregulated by viral infection, nutritional deficiency, TNF-α and oxidative stress in p2y inhibitor [44], [45] HSPs are classified in six families (including the HSP10, HSP40, HSP60, HSP70, HSP90 and HSP100 families). HSP90 [46] for example provid

• About epilepsy no specific seizure type

  2021-10-29

  

  About epilepsy, no specific seizure type has been identified because GLUT1-DS is associated with a wide range of epilepsies: patients develop seizures in infancy and early childhood, which are, frequently, do not respond to anticonvulsant medication. In infants, seizures are described as brief, subt

• br Acknowledgements br Introduction Glucagon a amino

  2021-10-29

  

  Acknowledgements Introduction Glucagon, a 29-amino 5-Carboxymethylester-UTP peptide, is released from the pancreatic islets, intestine and stomach. Glucagon is released under hypoglycemic conditions and then elevates blood glucose levels, serving as a major counter hormone [1]. The regulation

• In a series of experiments the

  2021-10-29

  

  In a series of experiments, the clotrimazole concentration was varied and the NSVDC channel conductances were calculated from Eq. (1) to obtain the dose-response relation (Fig. 3). The data were fitted to the Michaelis–Menten-type activation curve (Eq. (3)) and gave an EC50 value of 14 μM and a dose

• br Conflict of interest statement br Introduction br Gap jun

  2021-10-29

  

  Conflict of interest statement Introduction Gap junction assembly Induced disassembly of gap junctions The regulation of connexin and gap junction turnover are still not well understood. This is, in part, due to the fact that while the overall turnover of connexin molecules is fairly con

• cholecystokinin receptor br Declaration of competing interes

  2021-10-29

  

  Declaration of competing interests Acknowledgements The authors wish to thank the Natural Science Foundation of Jiangsu Province (BK20171261), the project of outstanding scientific and technological innovation group of Jiangsu Province, the National Science Fund for Distinguished Young Scholar

• Moreover intestinal chronic inflammation is a promoting fact

  2021-10-29

  

  Moreover, intestinal chronic inflammation is a promoting factor in the development of CRC in patients affected by inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. We have previously shown that pharmacological FXR activation via its ligand obeticolic DMP 777 countera

• The primary cancer lesion was mostly in the

  2021-10-29

  

  The primary cancer lesion was mostly in the uterus and adnexa, followed by the gastrointestinal tract, brain, blood, and kidney and RJR-2403 oxalate (Fig. 2A). Histopathological findings indicated that most cancers were adenocarcinomas, followed by squamous cell carcinomas, glioblastomas, malignant

• BMP signals play pivotal roles in the various processes

  2021-10-29

  

  BMP signals play pivotal roles in the various processes of chondrogenesis [12], [13]. At early stages of chondrogenesis, BMP signaling regulates the differentiation of mesenchymal 20(S)-Hydroxycholesterol into chondrocytes via the induction of Sox9[29]. The loss of Noggin, a BMP antagonist, results

• GZD824 australia br Introduction Hepatitis B virus HBV

  2021-10-28

  

  Introduction Hepatitis B virus (HBV) infects about 2 billion people worldwide and is a leading cause of liver disease including liver fibrosis, cirrhosis and hepatocellular carcinoma (Trepo et al., 2014). Most current HBV therapies are based on nucleos(t)ide analogs and pegylated interferon alpha

• br Concluding remarks br Conflict of interest

  2021-10-28

  

  Concluding remarks Conflict of interest statement References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Acknowledgements We thank all the present and former members in our laboratory for their contributions to

16462 records 574/1098 page Previous Next First page 上5页 571572573574575 下5页 Last page