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The N terminal amino acid sequence was made for
2021-04-21

The N-terminal amino Cyanidin Chloride receptor sequence was made for STH2. This sequence showed high similarity (100%) with to trypsin-like found in the human airway classified as serine proteinase that also belongs to peptidase family SI and related also with chymotrypsin-like enzymes (Yasuoka et
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Some antioxidants including N acetylcysteine and SOD have be
2021-04-21

Some antioxidants, including N-acetylcysteine and SOD, have been shown to decrease collagen deposition and protect the lungs in various animal models and even in clinical trials (Chan et al., 2013, Loomis-King et al., 2013, Rafii et al., 2013, Teixeira et al., 2008, Wang et al., 2013). Bleomycin-ind
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As the angular structure of compound
2021-04-21

As the angular structure of compound cannot be differentiated from the linear structure by H NMR spectroscopy, a NOESY NMR experiment was performed to unambiguously characterize the regioselectivity of the final compound. In the linear compound , a signature correlation between the proton of the thi
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br Materials and methods br Results br Discussion Our
2021-04-21

Materials and methods Results Discussion Our previous investigation demonstrated that some genes in the latex that were involved in rubber biosynthesis were regulated by exogenous JA, and Hbvp1 is one of the JA-responsive genes in the latex of rubber trees [23]. In this study, the Hbvp1 enc
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br Materials and methods Male
2021-04-21

Materials and methods Male Hartley guinea pigs (300–350g) were obtained from National Laboratory Animal Center, Taiwan. LTD4, LTC4, LTE4, LTB4, montelukast and BAY u9773 were purchased from Cayman Chemical, Ann Arbor, Michigan; Carbachol, atropine, l-serine, boric acid, l-cysteine and all buffer
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van Linden et al developed a comprehensive guide that
2021-04-21

van Linden et al. developed a comprehensive guide that describes drug and ligand binding to more than 1200 human and mouse protein kinase domains [77]. Their KLIFS (kinase–ligand interaction fingerprint and structure) directory includes an alignment of 85 potential ligand binding-site residues occur
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Mass spectrometry has previously been
2021-04-21

Mass spectrometry has previously been used to examine the presence of Hyp in recombinant collagen, using hydrolysates to identify the individual imino acid, equivalent to an amino VX-702 receptor analysis [33], and also by analysis of mass changes to tryptic peptides [34]. The present study, howeve
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NPC L expression is both tissue
2021-04-21

NPC1L1 expression is both tissue- and species-specific. Consistent with its function, NPC1L1 is mainly localized to the brush border membrane of enterocytes and the canalicular membrane of hepatocytes. NPC1L1, which is expressed in the liver of humans and rats but not mice, mediates cholesterol caff
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Efaproxiral Sodium Exposure to UV instead of
2021-04-20

Exposure to UV instead of DMBA also produced a sloughing and angiogenic response in transgenic, but not WT, mice, indicating that the epidermis of the BK5.EP4 mice has a much lower apoptosis threshold than WT mice, as suggested by others (Chun and Langenbach, 2007). Overall, these studies suggest th
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br Materials and methods br Results Overexpression of
2021-04-20

Materials and methods Results Overexpression of KLF2 increased the cell viability and reduced the LDH leakage rate and O2•− and ONOO− generation in H/R HUVEC model. To evaluate the effect of KLF2 on H/R HUVEC injury, KLF2 was overexpressed in HUVECs. Cell viability and extracellular LDH level
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Introduction Cognitive impairment is a core stable feature
2021-04-20

Introduction Cognitive impairment is a core, stable feature of schizophrenia that limits patient functioning and well-being (Keefe and Harvey, 2012) and associates with poor functional outcome (Fervaha et al., 2014, Kontaxaki et al., 2014). Studies also indicate that cognitive deficits occur prior
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br Materials and methods br Statistical
2021-04-20

Materials and methods Statistical analysis All statistical analyses were performed using SPSS software version 20. Protein PF-670462 data of DNMTs and clinicopathological parameters were collected. Mann-Whitney U Test was used to assess the differential expression of nonparametric data of DNM
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ML347 Cysteine protease activities have been suggested to be
2021-04-20

Cysteine protease activities have been suggested to be important for Giardia’s pathogenesis [[11], [12], [13],16,18,19,21,28,29,35]. Recently several giardial CPs were shown to be released during host cell interactions [9,10]. The three major released CPs have recently been shown to be involved in t
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We also evaluated the influence of
2021-04-20

We also evaluated the influence of the number of CYP3A variant PI-3065 (n=0 to 3) on the modifying effects on MDI and PDI. No clear allele dosage effect could be observed (data not shown). Discussion Prior reports for all four populations showed that an increase in prenatal Hg was not adversely
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In rats exposed to day of nicotine withdrawal h after
2021-04-19

In rats exposed to 1 day of nicotine withdrawal (24 h after the last nicotine administration) we expected a decrease of general locomotor activity and a decrease of global striatal dopamine release, which were assessed in a previous study following 14 days of nicotine exposure and 24 h of nicotine
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